Abstract #2345
Real-time Monitoring of Focused Ultrasound Inertial Cavitationon on Microbubbles by Gradient Echo MRI
Chen-Hua Wu 1 , Chih-Kuang Yeh 1 , Chung-Hsin Wang 1 , Shih-Tsung Kang 1 , Wen-Shiang Chen 2,3 , and Hsu-Hsia Peng 1
1
Department of Biomedical Engineering and
Environmental Sciences, National Tsing Hua University,
Hsinchu, Taiwan,
2
Department
of Physical Medicine and Rehabilitation, National Taiwan
University Hospital, Taipei, Taiwan,
3
Division
of Medical Engineering Research, National Health
Research Institutes, Miaoli, Taiwan
In this study, a gradient echo based sequence was used
to observe the signal intensity (SI) changes during FUS
cavitation for in vitro gel phantom experiments. We
investigated SI changes under different concentrations
of MBs, FUS powers, and imaging slice thicknesses. Even
with conditions of diluted MBs of 0.001X, low FUS power
of 2W in a burst mode, or thicker slice of 8 mm, reduced
SI still can be observed. The pulse sequence of gradient
echo has been proved to be a useful technique for
real-time monitoring of SI changes when transmitting FUS
to MBs.
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