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Abstract #2309

Preliminary Lung Density Measurements with a Portable Low-Filed System

Mikayel Dabaghyan 1 , Iga Muradyan 2 , Angelos Kyriazis 2 , Alan Hrovat 1 , James P Butler 2 , Samuel Patz 2 , and Mirko Hrovat 1

1 Mirtech Inc, Brockton, MA, United States, 2 Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States

Here we present initial in vivo lung density measurements at three different lung volumes using a portable low field NMR system built in our lab. The measurements are proportional to lung density. As one predicts, the signal decreases with increasing lung volume. The measurements were highly reproducible with std < 12%. The SNR in a single 40s breath-hold at TLC was measured to be over 110. We also report initial hyperpolarized Xe measurements in a phantom using the same system with high SNR observed in a single data acquisition.

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