Abstract #2298
High-resolution MRI of hyperpolarized propane at 4.7 T and 0.0475 T
Kirill V Kovtunov 1 , Milton L Truong 2 , Aaron M Coffey 2 , Danila A Barskiy 1 , Igor V Koptyug 1 , Kevin W Waddell 2 , and Eduard Y. Chekmenev 2
1
International Tomography Center,
Novosibirsk, Novosibirsk, Russian Federation,
2
Radiology,
Vanderbilt University, Nashville, TN, United States
Fast (TR<4 ms) hyperpolarized proton MRI is presented
for non-toxic propane gas prepared by heterogeneous
parahydrogen induced polarization using Rh/TiO
2
solid
state catalyst. 3D imaging with 0.5x0.5x0.5 mm
3
is
demonstrated using ~1% 1H hyperpolarized propane at 4.7
T preclinical MRI system with relatively large field of
view 48x48x32 mm
3
. Feasibility of sub-second
sub-millimeter (0.9x0.9 mm
2
) 2D imaging of
hyperpolarized propane (polarization P=0.3%) is also
demonstrated at 0.0475 T preclinical MRI using frequency
optimized RF coils. Hyperpolarized propane MRI can
potentially be used for economical high-throughput
low-field functional MRI of human lungs.
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