Magnetization Transfer Effect in the Lung Parenchyma: Dependence on the Presence of the Blood Signal
Pavla Francov 1,2 , Flavio Carinci 1,2 , Simon Triphan 1,3 , and Peter M. Jakob 1,2
Research Center Magnetic Resonance Bavaria
e. V. (MRB), Wrzburg, Germany,
of Experimental Physics 5, University of Wrzburg,
Department of Diagnostic
and Interventional Radiology, University Hospital
Heidelberg, Heidelberg, Germany
Magnetization Transfer (MT) is a promising tool for the
characterization of the lung parenchyma and thus lung
diseases, where e.g. the collagen content is increased.
Since the mechanisms of MT in the lungs are rather
unknown we investigated the influence of blood in the
lung parenchyma on the MT effect. For this
MTC-measurements were performed on the bloodless pig
lungs and healthy volunteers group in a 1.5T scanner.
The major finding was that blood has a significant
influence on the MT effect.
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