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Abstract #2296

Magnetization Transfer Effect in the Lung Parenchyma: Dependence on the Presence of the Blood Signal

Pavla Francov 1,2 , Flavio Carinci 1,2 , Simon Triphan 1,3 , and Peter M. Jakob 1,2

1 Research Center Magnetic Resonance Bavaria e. V. (MRB), Wrzburg, Germany, 2 Department of Experimental Physics 5, University of Wrzburg, Wrzburg, Germany, 3 Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany

Magnetization Transfer (MT) is a promising tool for the characterization of the lung parenchyma and thus lung diseases, where e.g. the collagen content is increased. Since the mechanisms of MT in the lungs are rather unknown we investigated the influence of blood in the lung parenchyma on the MT effect. For this MTC-measurements were performed on the bloodless pig lungs and healthy volunteers group in a 1.5T scanner. The major finding was that blood has a significant influence on the MT effect.

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