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Abstract #2255

Reduction of cardiac motion-related effects on liver diffusion imaging

Diego Hernando 1 , Utaroh Motosugi 1,2 , Peter Bannas 1,3 , Samir D. Sharma 1 , and Scott B. Reeder 1,4

1 Radiology, University of Wisconsin-Madison, Madison, WI, United States, 2 Radiology, University of Yamanashi, Yamanashi, Japan, 3 Radiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany, 4 Medicine, University of Wisconsin-Madison, Madison, WI, United States

Cardiac motion-related effects are severe in liver diffusion MRI, where they introduce signal voids in diffusion-weighted images (particularly in the left liver lobe) and result in errors and high variability in ADC measurements. This variability has precluded the widespread application of quantitative liver diffusion MRI. In this work, we characterize cardiac motion effects on liver diffusion imaging, and assess simple correction techniques to reduce variability in ADC maps by taking maximum intensity over multiple signal acquisitions (ADCMIP), in which we hypothesized we could exclude signals affected by cardiac motion. The ADCMIP was less affected by cardiac-motion than conventional ADC maps.

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