Meeting Banner
Abstract #2243

Assessment of reproducibility of IVIM based perfusion fraction and diffusion coefficient in the pancreas

Oliver J. Gurney-Champion 1 , Martijn Froeling 2 , Remy Klaassen 1 , Jaap Stoker 1 , Geertjan van Tienhoven 1 , Hanneke W.M. van Laarhoven 1 , Arjan Bel 1 , and Aart J. Nederveen 1

1 Academic Medical Center, Amsterdam, Netherlands, 2 University Medical Center Utrecht, Netherlands

The perfusion fraction, f, obtained from intravoxel incoherent imaging can potentially be used as biomarker to distinguish between pancreatic carcinomas and healthy tissue. Using an optimized imaging sequence, together with an in-house post-processing toolkit in eight healthy volunteers, we show a good reproducibility for f (RI=17%) and diffusion coefficient, D, (RI=13%). Averaging over all volunteers we found D=1.400.07x10-3 mm3/s, f=9.41.8 % and pseudo-diffusion coefficient D*=0.0871 mm3/s . We showed how the RI decreases for decreasing number of averages. Finally, for one patient, we could observe a difference in f between healthy and tumorous pancreas tissue.

This abstract and the presentation materials are available to members only; a login is required.

Join Here