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Abstract #2226

Evaluating placental growth in normal murine pregnancy using tissue-similarity-mapping and dynamic contrast enhanced magnetic resonance imaging

Brijesh Kumar Yadav 1,2 , Uday Bhaskar Krishnamurthy 1,2 , Yimin Shen 1 , Jaladhar Neelavalli 1,2 , Gabor Szalai 3 , Bing Wang 3 , Tinnakorn Chaiworapongsa 3,4 , Edgar Hernandez-Andrade 3,4 , Nandor Gabor Than 3,4 , Ewart Mark Haacke 1,2 , and Roberto Romero 3

1 Department of Radiology, Wayne State University, Detroit, Michigan, United States, 2 Department of Biomedical Engineering, Wayne State University, Detroit, Michigan, United States, 3 Perinatology Research Branch, NICHD, NIH, DHHS., Wayne State University, Detroit, Michigan, United States, 4 Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan, United States

In this study, the longitudinal variations in the size of high perfusion and low perfusion zones of the normal murine placenta along different gestational ages are quantified using dynamic contrast enhancement magnetic resonance imaging(DCE-MRI) and an automatic segmentation method based on Tissue Similarity Mapping (TSM.

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