Abstract #2196
Optimal measurement of arterial input function in MR renography using saturation recovery
Christopher C. Conlin 1 , Jeff L. Zhang 1 , Marta E. Heilbrun 1 , Kristi Carlston 1 , Daniel Kim 1 , Kathryn A. Morton 1 , and Vivian S. Lee 1
1
Department of Radiology, University of Utah,
Salt Lake City, Utah, United States
This study compares long and short inversion times (TIs)
for measuring arterial input functions (AIFs) from
saturation recovery images in the estimation of
glomerular filtration rate (GFR) from low dose Gd-enhanced
MR renography. Long TIs may result in saturated signal
and therefore an inaccurate estimate of Gd concentration
which is required for GFR calculation. Short TIs may
suffer from low SNR. By comparing GFR estimates obtained
at short and long TIs to reference measurements from
99mTc-DTPA clearance, it was found that relatively long
TIs should be used to avoid accumulation of AIF error
into the estimated GFR.
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