Abstract #2190
Arterial transit time-corrected renal blood flow measurement by pulsed continuous arterial spin labeling MRI: a feasibility and validation study in healthy volunteers
Kazuhiro Shimizu 1 , Nobuyuki Kosaka 1 , Yasuhiro Fujiwara 1 , Tsuyoshi Matsuda 2 , Tatsuya Yamamoto 1 , Tatsuro Tsuchida 1 , Katsuki Tsuchiyama 3 , Nobuyuki Oyama 3 , and Hirohiko Kimura 1
1
Department of Radiology, University of
Fukui, Eiheiji, Fukui, Japan,
2
Global
MR Applications and Workflow, GE Healthcare Japan, Hino,
Tokyo, Japan,
3
Department
of Urology, University of Fukui, Eiheiji, Fukui, Japan
We evaluated the feasibility of pulsed continuous
arterial spin labeling (pcASL) MRI with multiple
post-label-delay (PLD) acquisition for measuring
arterial transit time (ATT)-corrected renal blood flow (ATC-RBF)
in healthy volunteers. Significant differences were seen
between younger and older groups in ATC-RBF and ATT, and
kidney volume-corrected ATC-RBF (ATC-cRBF) correlated
significantly with effective renal plasma flow (ERPF),
as measured by 99mTc-MAG3 scintigraphy. However, the
only moderate correlation between ATC-cRBF and ERPF
suggests that further technical development may be
required for RBF quantification by pcASL MRI.
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