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Abstract #2169

Extracting arterial to portal hepatic flow ratio using high frame rate Gd MRI

Lorne W Hofstetter 1 , Mitchell A Cooper 1 , Silvina P Dutruel 1 , Mahajabin Rahman 1 , Shan Hu 1 , Nandadeepa Thimmappa 1 , Pascal Spincemaille 1 , Yi Wang 1 , and Martin R Prince 1

1 Radiology, Weill Cornell Medical College, New York, New York, United States

On time-resolved contrast enhanced MRI, a cirrhotic liver tends to enhance less and more slowly than the normal liver. In addition, it is well known that the ratio of arterial to portal blood supply for the liver increases in cirrhosis. In previous approaches, a separate 2D contrast enhanced exam was necessary to sample the liver enhancement curve with high temporal resolution, complicating the integration of this method into clinical practice. We hypothesize that these differences in liver perfusion between normal and cirrhotic liver can be detected using a high frame rate 3D contrast enhanced MRI of the liver obtained with the TRACER method.

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