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Abstract #2151

Hepatic MR Elastography by Using Optimized Flexible Drivers

Jun Chen 1 , Kevin Glaser 1 , Meng Yin 1 , Jayant Talwalkar 1 , Phillip Rossman 1 , Sudhakar Venkatesh 1 , and Richard Ehman 1

1 Mayo Clinic, Rochester, MN, United States

Hepatic MR Elastography (MRE) is an accurate noninvasive method for detecting liver fibrosis. Conventional drivers for hepatic MRE are usually rigid, but human bodies are soft and contoured. Therefore, the mechanical coupling between rigid drivers and human body is often not optimal, resulting in potential issues such as wave interferences in the liver. Previous developed hepatic flexible driver was optimized in this study for higher efficiency. Patients with a large range of liver fibrosis stage underwent MRE with both the flexible and rigid drivers. The mean difference was 0.11kPa, indicating that both drivers are equivalent for measuring liver stiffness.

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