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Abstract #2149

The value of severe liver iron overload to predict cardiac iron level

Xiaodong Chen 1,2 , Hui Zhang 3 , Xihai Zhao 3 , Huailing Zhang 4 , Biling Liang 5 , and Hua Guo 3

1 Sun Yat-Sen Memorial Hospital, Guangzhou, Guangdong, China, 2 Guangdong Medical College, Guangdong, China, 3 Biomedical Engineering&Center for Biomedical Imaging research,School of Medicine,Tsinghua University, Beijing, China, 4 School of Information Engineering, Guangdong Medical College, Guangdong, China, 5 Sun Yat-Sen Memorial Hospital, Guangdong, China

Cardiac failure is the main causes of death in patients with thalassemia major 1,2. But its diagnosis is often hysteretic in clinical practice, which probably in consequence of the unpredictability of cardiac iron deposition as well as the lag of appearance of symptoms, Thus, it is vital to monitor the cardiac iron level even in asymptomatic patients. Hepatic iron concentration has been widely used as the indicator of this disease. However, it lacks extensive investigation about the relationship between hepatic iron overload and myocardium iron overload, especially when the liver has severe deposition.

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