Abstract #1878
Towards clinical implementation of IVIM analysis in brain tumors: Influence of cerebrospinal fluid contamination on the perfusion fraction
Sotirios Bisdas 1 , Christian Braun 2 , Ulrike Ernemann 1 , and Uwe Klose 1
1
Neuroradiology, Eberhard Karls University,
Tbingen, Germany,
2
Neurology,
Eberhard Karls University, Germany
The dependence of perfusion fraction (f) on CSF in IVIM
analysis of brain can be demonstrated by DWI
measurements with 2 different TEs. The f in cortical or
juxta-cortical regions was higher in measurements with
longer TE indicating that the fast decaying signal
component had long T2, as expected for CSF. In white
matter and tumor tissue, f showed no dependence on TE.
Considering the influence of CSF on f values and the
robustness of the method in lesions located in white
matter and tumors is very important prior to any
clinical dissemination of IVIM analysis in brain
pathologies.
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