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Abstract #1865

Correlations of Structural and Functional Connectivity Alterations in Primary Motor Cortex in a Macaque Model of Ischemic Stroke

Yuguang Meng 1 , Frank Tong 2 , Chunxia Li 1 , Stuart Zola 1 , Leonard Howell 1 , and Xiaodong Zhang 1

1 Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States, 2 School Of Medicine, Emory University, Atlanta, GA, United States

Structural and functional alterations in primary motor cortex are generally observed in stroke patients and animal models. However, the temporal correlation between the both alterations after stroke insult is not completely understood. By using diffusion MRI and resting-state fMRI (rsfMRI), the correlation between the ipsilateral structural damage and interhemispheric functional connectivity alterations in primary motor cortex was evaluated with a macaque model of ischemic stroke.

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