Abstract #1838
Determination of CMRO2 changes During Hyperbaric Exposure
Damon P Cardenas 1 , Eric Muir 1 , Shiliang huang 2 , and Timothy Duong 1
1
Radiology, University of Texas Health
Science Center at San Antonio, San Antonio, Texas,
United States,
2
MRI,
Research Imaging Institute, San Antonio, Texas, United
States
The evaluation of CMRO2 at hyperbaric conditions is
pivotal to the understanding of the physiological
benefits of hyperbaric treatments. We evaluated
forepaw-evoked BOLD and CBF responses simultaneously in
rats under i) normobaric air, ii) normobaric oxygen,
iii) hyperbaric air, and iv) hyperbaric oxygen (HBO).
CMRO2 was determined using the aforementioned
parameters. Despite interesting physiological response
to CO2 challenges at high pressures, no significant
differences were identified across conditions, implying
the increased oxygen may be in excess of metabolic
demand.
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