Abstract #1786
Exploring the laminar components of the human cortex using ultra-high resolution Inversion Recovery and diffusion
Daniel Barazany 1,2 , Karl Zilles 3 , and Yaniv Assaf 1
1
Department of Neurobiology, Tel Aviv
University, Tel Aviv, Israel,
2
CUBRIC
School of Psychology, Cardiff University, Cardiff,
United Kingdom,
3
Institute
of Neuroscience and Medicine INM-1, Research Center
Juelich, Jeulich, Germany
Inversion recovery (IR) MRI provide image contrasts that
allow the human cortex segmentation to their
subcomponents (i.e., IR-layers), based on the intrinsic
T1 properties. In this work, several tissue blocks of
fixed human cortex were scanned at ultra-high resolution
both IR-MRI to visualize their IR layers. In addition,
we also acquired different diffusion MRI modalities such
as diffusion tensor imaging (DTI) and composite hindered
and restricted model of diffusion (CHARMED) to explore
the IR-layer diffusion characteristics and their
connectivity patterns by tractography analysis.
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