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Abstract #1725

Preliminary Investigation of Ultrashort T2* in Healthy Cervical Cord Grey Matter and White Matter In Vivo at 3T

Marios C. Yiannakas 1 , Bhavana S. Solanky 1 , Frank Riemer 1 , Daniel J. Tozer 1 , Hugh Kearney 1 , David H. Miller 1 , and Claudia A. M. Wheeler-Kingshott 1

1 Neuroinflammation, UCL - Institute of Neurology, London, London, United Kingdom

In this work the feasibility of using ultrashort echo time (UTE) imaging to obtain T2* measurements in grey matter (GM) and white matter (WM) independently within the upper cervical cord in vivo is investigated. A linear fit of the natural logarithm in two echo times (2-point fit) is used for the measurements. The results show a distinct difference in T2* between GM and WM which is suggestive of differences in macromolecular structure. The method presented is clinically practical and maybe used in the future to study neurological disease affecting the spinal cord.

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