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Abstract #1699

Multiparametric Analysis using pCASL, IVIM and DKI for Head and Neck Squamous Cell Carcinoma

Noriyuki Fujima 1 , Daisuke Yoshida 1 , Tomohiro Sakashita 1 , Akihiro Homma 1 , Yuriko Suzuki 2 , and Kohsuke Kudo 1

1 Hokkaido University Hospital, Sapporo, Hokkaido, Japan, 2 Philips Electronics Japan, Tokyo, Japan

Tumor diffusion and perfusion is important factor for the assessment of head and neck squamous cell carcinoma (HNSCC). The aim of this study was to evaluate diagnostic value of the pCASL, IVIM and DKI as multi-parametric analysis in non-surgically treated HNSCC by assessing its usefulness as predictor of local control of primary tumor. This study revealed that noninvasive multiparametric evaluation by combining pCASL, IVIM, and DKI can provide high diagnostic accuracy to determine whether successful local control of primary tumor was obtained or not in HNSCC.

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