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Abstract #1692

Power-Law Multi-Frequency MRE Reconstruction

Elijah EW Van Houten 1 , Curtis L Johnson 2 , Aaron T Anderson 2 , Joseph L Holtrop 2 , Bradley P Sutton 2 , John G Georgiadis 2 , Matthew D McGarry 3 , John B Weaver 3 , and Keith D Paulsen 3

1 Univ. de Sherbrooke, Sherbrooke, QC, Canada, 2 Univ. Illinois at Urbana-Champaign, IL, United States, 3 Dartmouth College, NH, United States

A multi-frequency magnetic resonance elastography image reconstruction method is presented with power-law frequency dependency for the elastic properties. The method is based on a nonlinear inversion framework and uses a generalized Rayleigh damping model for the soft tissue elastic energy absorption. Comparative reconstructions in a healthy brain, based on three frequencies of excitation, show improved fidelity and definition within the power-law multi-frequency image. Structures such as the ventricles and the falx cerebri are clearly defined and possess material property values in line with expectations.

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