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Abstract #1689

MR-Rheology - A feasibility study with phantoms

Anna-Lisa Kofahl 1 , Jakob Bindl 1 , Deniz Ulucay 1 , Sebastian Theilenberg 1 , Judith Wild 1 , Sylvia Napiletzki 1 , Alexandra Vohlen 1 , Jrgen Finsterbusch 2 , Bernd Weber 3 , Carsten Urbach 1 , and Karl Maier 1

1 HISKP, University of Bonn, Bonn, Germany, 2 University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 3 Life & Brain GmbH, Bonn, Germany

The knowledge of the viscoelastic properties of the human brain tissue may aid in the diagnosis of diseases like Alzheimers disease, brain cancer or multiple sclerosis. A novel method to image the viscoelastic properties of the brain in vivo and non-invasively with a good spatial resolution is Magnetic Resonance Rheology (MR-R). MR-R uses an acceleration and creep experiment inside an MRI, where a motion encoding EPI sequence is used to measure the relaxation movement of the substance under investigation. To prove the feasibility of this novel method and to estimate its potential agar-phantoms with and without inclusions are investigated.

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