Motion Correction in Diffusion-Weighted Imaging using Intermediate Pseudo-Trace-Weighted Images

This paper introduces a new motion-correction technique for high-angular-resolution diffusion imaging studies. The method uses an optimized set of diffusion gradient vectors, which allows intermediate images to be calculated with a contrast that approximates to that of a trace-weighted image. The low contrast variation makes these intermediate images useful for motion tracking during the time series. Studies in healthy subjects suggest that the method delivers motion parameter estimates that are similar to those provided by interleaved low-b-value images. The temporal resolution can be optimized by using a sliding-window method, in which the intermediate image is updated after each diffusion-weighted volume.

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