Abstract #1588
EPI distortion correction for quantitative imaging of the mouse brain at ultrahigh magnetic field
Xuan Vinh To 1 , Xin Hong 1 , Irvin Teh 2 , Jian Rui Soh 1 , and Kai-Hsiang Chuang 1
1
Lab of Molucular Imaging, Singapore
Bioimaging Consortium, Singapore, Singapore, Singapore,
2
A*STAR
- NUS Clinical Imaging Research Centre, Singapore,
Singapore
Echo Planar Imaging (EPI) is an ultrafast acquisition
technique widely used in fMRI, diffusion imaging and
perfusion imaging but suffers from geometric and
intensity distortions, especially in ultrahigh field
strength used in small animal imaging. In this study we
compared several distortion correction methods. We found
using a pair of reference EPI images acquired with
opposite phase encoding directions to calculate an
unwrapping field provides the most accurate, robust and
efficient distortion correction for the mouse brain.
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