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Abstract #1503

Multiband spin- and gradient-echo (SAGE) fMRI

Heiko Schmiedeskamp 1 , Eric Peterson 1 , Julian Maclaren 1 , Rafael O'Halloran 1 , Thomas Christen 1 , Samantha J Holdsworth 1 , Eric Aboussouan 1 , William A Grissom 2 , and Roland Bammer 1

1 Department of Radiology, Stanford University, Stanford, CA, United States, 2 Biomedical Engineering, Vanderbilt University, Nashville, TN, United States

The combined acquisition of gradient-echo and spin-echo fMRI signals facilitates the differentiation between simultaneously acquired BOLD signal changes with distinct contrast mechanisms at the expense of increased repetition time or decreased slice coverage. To facilitate combined gradient-echo and spin-echo fMRI while maintaining whole-brain coverage without prolonging TR, we propose utilizing multiband RF excitation in simultaneous multi-echo spin- and gradient-echo (SAGE) EPI acquisitions for fMRI, and we present preliminary results using a breath-hold task as proof-of-principle for stimulus-based multiband SAGE fMRI experiments.

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