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Abstract #1489

7D velocity phase imaging with zoomed simultaneous multi-slice EPI reveals respiration driven motion in brain and CSF

Liyong Chen 1,2 , Alexander Beckett 1,2 , Ajay Verma 3 , and David Feinberg 1,2

1 Helen Wills Neuroscience Institute, University of California, Berkeley, California, United States, 2 Advanced MRI Technologies, LLC, Sebastopol, California, United States, 3 Biogen Idec, MA, United States

A new highly efficient velocity imaging technique is developed with simultaneous multi-slice EPI and zoomed spatial resolution which enables real-time measurement of CSF and brain velocity. Application of this 7D imaging technique to normal subjects revealed respiratory synchronous motion modulating cardiac waveforms in brain parenchyma and CSF. The brain pulsations may play a role in clearance of interstitial fluid in the brain.

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