Abstract #1487
Accurate And Reliable PC-MRI Sequence To Investigate Complex Dynamic Of Cerebro-Spinal Fluid in the Brain.
Malek I Makki 1 , Christoph Ruegger 2 , Cyrille Capel 3 , Catherine Gondry-Jouet 4 , and Olivier Baledent 5
1
MRI Research Center, University Children
Hospital of Zurich, Zurich, Switzerland,
2
Neonatalogy,
University Hospital of Zurich, Zurich, Switzerland,
3
Neurosurgery,
University Hospital, Amiens, France,
4
Radiology,
University Hospital, Amiens, France,
5
Image
Processing, University Hospital, Amiens, France
An accurate CSF flow measurement through the pontine
cistern is difficult to achieve because of blood flow
artifacts from the basilar artery and surrounding
vessels. We developed a dedicated PCMRI sequence with
pre-saturation double sided bands to suppress signal
from blood with no compromise neither on SNR nor on
spatio-temporal resolution and validated this on 18
patients with hydrocephalus. We compared the results of
the developed sequence in the pontine cistern and
foramen of Magendi which is free of blood flow artifact
and demonstrated its accuracy and reliability to
measuring the stroke volume and the minimum and maximum
flow.
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