Abstract #1437
Detection of hepatic glycogen by 1D ISIS localized 13 C MRS at 7T.
Martin Krssak 1,2 , Martin Gajdosik 2 , Ladislav Valkovic 2 , Wolfgang Bogner 2 , Michael Krebs 1 , Anton Luger 1 , Siegfried Trattnig 2 , and Marek Chmelik 2
1
Division of Endocrinology and Metabolism,
Department of Internal Medicine III, Medical University
of Vienna, 1090, Austria,
2
High
Field MR Centre, Department of Biomedical Imaging and
Image-Guided Therapy, Medical University of Vienna,
Wien, Austria
The aim of this study was to introduce and test the
13
C
MRS localization scheme suitable for the measurement of
hepatic glycogen at 7T in short acquisition time. One
dimensional slice selective version of recently
introduced fully adiabatic extended ISIS sequence was
proposed and tested on phantom and in vivo on healthy
volunteers. 1D ISIS scheme applied at 7T presented
optimal localization performance and sufficient signal
to noise of natural abundance 1-
13
C hepatic
glycogen doublet in relatively short acquisition times
(416).
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