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Abstract #1426

Tractography of the trigeminal nerve using 7T MRI

Christophe Lenglet 1 , Julien Sein 1 , Julian Tokarev 2 , Andrew W Grande 3 , Bharathi Jagadeesan 4 , and Pierre-Francois Van de Moortele 1

1 Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 2 University of Minnesota, Minneapolis, MN, United States, 3 Department of Neurosurgery, University of Minnesota, Minneapolis, MN, United States, 4 Department of Radiology, University of Minnesota, Minneapolis, MN, United States

We performed ultra high-field (7T) diffusion MRI and probabilistic tractography on the trigeminal nerve in a series of normal volunteers. We were able to reconstruct the detailed three-dimensional course of fiber pathways from individual divisions of the trigeminal nerve, as they travel within its ganglion and the nerve root to the brain stem. This information can be useful to better understand the etiology of Trigeminal Neuralgia, a poorly understood neurological disorder, which is characterized by extremely painful episodes of facial pain produced by routine stimuli like light touch.

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