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Abstract #1412

Clinical Application of 7T MRI for Deep Brain Stimulation (DBS) Surgery and Postoperative Programming

Yuval Duchin 1 , Guillermo Sapiro 2 , Shai Chazin 1 , Kenneth Baker 3 , Jon McIver 4 , Jerrold Vitek 3 , and Noam Harel 1,5

1 Radiology / CMRR, University of Minnesota, Minneapolis, Minnesota, United States, 2 Electrical and Computer Engineering, Duke University, Durham, North Carolina, United States, 3 Neurology, University of Minnesota, Minneapolis, Minnesota, United States, 4 Neurosurgery, Regions Hospital, St. Paul, Minnesota, United States, 5 Neurosurgery, University of Minnesota, Minneapolis, Minnesota, United States

Deep brain stimulation (DBS) surgery has emerged as a powerful neuromodulation clinical therapy. Current standard clinical imaging protocols do not have sufficient resolution and/or SNR to delineate brain structures relevant to DBS surgery. Structural images acquired at 7T exhibit rich informational content with potential utility for clinical applications. Here we utilized 7T images to create patient-specific anatomical models to enhance pre-surgical DBS targeting as well as post-surgical visualization of the DBS lead position and orientation, including its four individual contacts. These new visualization capabilities will enhance and improve DBS outcomes.

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