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Abstract #1345

Endoluminal MRI coils for mice rectal wall assessment

Hugo Dorez 1 , Raphal Sablong 1 , Laurence Canaple 2 , Sophie Gaillard 1 , Driffa Moussata 3 , and Olivier Beuf 1

1 Universit de Lyon, CREATIS CNRS UMR 5220 INSERM U1044 INSA Lyon 1, Villeurbanne, Rhne-Alpes, France, 2 Institut de Gnomique Fonctionnelle de Lyon, Universit de Lyon 1, UMR 5242 CNRS, Ecole Normale Suprieure de Lyon, Lyon, Rhne-Alpes, France, 3 Service hpato-gastroentrologie, Hospice Civil Lyon Sud, Pierre-Bnite, Rhne-Alpes, France

The purpose of this project research is to assess mice rectum wall using MRI combined with endomicroscopy and conventional endoscopy. Endoluminal MRI coils with active decoupling circuit were developed and characterized on phantoms. Then, in-vivo examination was finally done on mice (c57 black6j). Endoluminal coils improve significantly the local SNR compared to body mice volume birdcage coil. Rectal wall layers are better visualized due to improved spatial resolution achieve with SNR gain. This study shows the feasibility to use small endoluminal coils for mice rectal wall assessment and opens perspectives to better understand rectal pathologies.

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