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Abstract #1328

Spatial Normalization Can Morph RF Coils into Geometries Optimized for fcMRI Studies in Specific Brain Regions

Iain P Bruce 1 , L Tugan Muftuler 2,3 , and Daniel B Rowe 1,2

1 Mathematics, Statistics and Computer Science, Marquette University, Milwaukee, WI, United States, 2 Biophysics, Medical College of Wisconsin, WI, United States, 3 Center of Imaging Research, Medical College of Wisconsin, WI, United States

Many degenerative brain disorders are commonly associated with specific regions of the brain that are often off-center and can reside within aliased regions prior to a SENSE reconstruction. While a conventional array of rectangular coils may generate the most uniform magnetic field sensitivities throughout the brain, the human brain is not symmetric, and such sensitivities may not be optimal for fcMRI studies in all regions. This study proposes an approach of using spatial normalization together with an iterated conditional modes algorithm to morph an array of rectangular coils into a geometry that is more optimal for a specific ROI.

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