Meeting Banner
Abstract #1271

A novel method for quantifying inflammation of sacroiliitis in juvenile arthritis

Kanimozhi Vendhan 1 , David Atkinson 2 , Debajit Sen 3 , Corinne Fisher 3 , Yiannis Ioannou 4 , Paul Bassett 5 , and Margaret Hall-Craggs 6

1 UCLH, London, London, United Kingdom, 2 UCL, London, United Kingdom, 3 UCLH, London, United Kingdom, 4 Arthritis Research UK Centre for Adolescent Rheumatology, UCL, London, United Kingdom, 5 Statsconsultancy Ltd, London, United Kingdom, 6 Imaging Department, UCLH, London, United Kingdom

This was a retrospective case-control study to quantify sacroiliitis in patients with juvenile arthritis by using ADC maps. Along with conventional sequences, DWI of the sacroiliac joints (SIJs) was performed at multiple b values. A Matlab program was written to create a profile of ADC values across the SIJs and a reference sample in normal bone. This was done by manually drawing a multiple linear regions of interest, centered on the SIJ. There was a highly significant difference between the ADC area scores of the cases and controls. This novel technique for quantifying sacroiliitis could potentially be used to monitor response to therapy.

This abstract and the presentation materials are available to members only; a login is required.

Join Here