Abstract #1250
3D Model for MR Image Contrast in the Annulus Fibrosus of the Intervertebral Disc
Alexander C. Wright 1 , Edward J. Vresilovic 2 , and Dawn M. Ellliott 3
1
Laboratory for Structural NMR Imaging,
Department of Radiology, University of Pennsylvania,
Philadelphia, PA, United States,
2
Department
of Orthopaedics and Rehabilitation, Penn State
University, Hershey, PA, United States,
3
Department
of Biomedical Engineering, University of Delaware,
Newark, DE, United States
The purpose of this study is to provide a theoretical
model for the visibility (image contrast) of collagen
lamellae in the annulus fibrosus as seen in MRI. The
model is based on the assumption of a dipolar term in
the T2 relaxation mechanism of water protons and that
the observed anisotropic modulation of signal intensity
reflects the underlying microstructure of collagen
fibers.
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