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Abstract #1198

Morphologic MRI findings related to new pain development over a period of 4 years Data from the Osteoarthritis Initiative

Stephanie Hou 1 , Lorenzo Nardo 1 , Ursula Heilmeier 1 , Sonia Lee 1 , John Lynch 1 , Chuck McCulloch 1 , Gabby Joseph 1 , and Thomas Link 1

1 UCSF, San Francisco, CA, United States

This longitudinal study identified morphological MRI findings correlated with development of new pain over a period of 4 years in the knees of subjects at risk for osteoarthritis. The following findings were significantly associated with pain: baseline medial tibial cartilage pathology, baseline medial meniscus body pathology, incident effusion, and progressive patella cartilage pathology. Trends suggested an association of the following findings with pain: baseline medial tibia bone marrow edema pattern, medial femoral condyle bone marrow edema pattern at 4 years, and anterior medial meniscus pathology at 4 years. These associations may help radiologists to better guide clinical treatment.

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