Meeting Banner
Abstract #1189

Evaluation of the integration of silk fibroin ligament-like tissue into the bone after ACL reconstruction of the sheep model, using 7Tesla MR imaging.

Pavol Szomolanyi 1 , Andreas Teuschl 2,3 , Martin Brix 1,4 , Joachim Friske 1 , Vladimir Juras 1 , Xeni Deligianni 5 , Oliver Bieri 5 , Thomas Nau 6 , Heinz Redl 3,6 , and Siegfried Trattnig 1

1 Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, High Field MR Centre, Vienna, Vienna, Austria, 2 City of Vienna Competence Team Tissue Engineering Bioreactors, University of Applied Sciences Technikum Wien, Vienna, Austria, 3 The Austrian Cluster for Tissue Regeneration, Vienna, Austria, 4 Department of Orthopaedics, Medical University of Vienna, Vienna, Austria, 5 Department of Radiology, University of Basel Hospital, Division of Radiological Physics, Basel, Switzerland, 6 Ludwig Boltzmann Institute for clinical and experimental Traumatology, Vienna, Austria

Most promising materials for ACL reconstruction are based on silk fibroin as scaffold material. Surprisingly, there is still a lack of knowledge on the integration of silk fibroin scaffolds into bone. Thus, the goal of this study was to evaluate the integration of silk fibroin into the bone by using MRI UTE sequence. MR analysis demonstrated that after 6 months the silk scaffolds were surrounded by soft tissue that further developed to the tight osteointegration. Our study show that UTE is the technique of choice for MR imaging of the very short T2* tissues.

This abstract and the presentation materials are available to members only; a login is required.

Join Here