Meeting Banner
Abstract #1061

Carbon Ion Radiation Therapy for Patients with Localized Prostate Cancer:

Maya B Wolf 1 , Timur H Kuru 2 , Gregor Habl 3 , and Matthias C Roethke 1

1 Radiology, DKFZ, Heidelberg, Baden-Wrttemberg, Germany, 2 Urology, University Hospital Heidelberg, Heidelberg, Baden-Wrttemberg, Germany, 3 Radiation Oncology, University Hospital Heidelberg, Heidelberg, Baden-Wrttemberg, Germany

Purpose was to assess T2- and diffusion-weighted imaging (DWI) after carbon ion therapy (CIT) of prostate cancer (PCa) for treatment monitoring. Multiparametric MRI including T2 and DWI at 3T were acquired prior to and following CIT in patients with histologically confirmed PCa. Statistical analysis of region of interest data showed T2w signal loss at the 6 months interval and immediate, as well as, continuous apparent diffusion coefficient (ADC) increase after treatment in PCa areas. PSA was inversely correlated with ADC values. The results suggest that ADC could serve as an imaging biomarker for assessing therapeutic response of PCa to CIT.

This abstract and the presentation materials are available to members only; a login is required.

Join Here