Abstract #1046
A novel and affordable DCE-MRI phantom: Prospective assessment of DCE-MRI breast protocols
Araminta E. W. Ledger 1 , Marco Borri 1 , Hector Sanchez Casas 1 , Craig Cummings 1 , Maria A. Schmidt 1 , and Martin O. Leach 1
1
CR-UK and EPSRC Cancer Imaging Centre, The
Institute of Cancer Research and Royal Marsden NHS
Foundation Trust, Sutton, Surrey, United Kingdom
DCE-MRI is an established component of breast screening
protocols, and uses the empirical classification of
contrast agent (CA) enhancement curves to aid diagnosis.
However, CA enhancement curves resulting from varying
parameter selections are difficult to assess
prospectively. This abstract uses a novel and affordable
DCE-MRI phantom to assess the effect of common sequence
alterations (CA injection timing and k-space sampling
scheme) on the CA enhancement curves obtained from two
clinical DCE-MRI sequences. Both CA injection timing and
k-space sampling pattern resulted in measurable curve
differences - sequence comparison with this phantom can
therefore help to establish robust DCE-MRI breast
protocols.
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