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Abstract #1043

Correlation of percent breast density with background parenchymal enhancement measured in MRI

Jeon-Hor Chen 1,2 , Yifan Li 1 , Hon Yu 1 , Shadfar Bahri 1 , Rita S Mehta 3 , and Min-Ying Su 1

1 Center for Functional Onco-Imaging, University of California, Irvine, California, United States, 2 Department of Radiology, Eda Hospital and I-Shou University, Kaohsiung, Taiwan, 3 Department of Medicine, University of California, Irvine, California, United States

In this study we aimed to correlate percent breast density (PD) and background parenchymal enhancement (BPE) in the contralateral normal breast (CNB) of patients diagnosed with breast cancer. Breast MR images of the CNB of 117 patients were studied. The quantification of the fibroglandular tissue volume (FV) was based on a computer-assisted algorithm. The mean BPE and the hot spot enhancement were correlated with age, and also with FV and PD. Our study showed that BPE, measured by the averaged enhancement of the whole FV or by hot spot, did not correlate well with quantitative measurement of PD and FV.

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