Meeting Banner
Abstract #1032

Diffusion MRI and in-vivo proton MR Spectroscopy Study of the Differentiation of Malignant Breast Tissue of Breast Cancer Patients and the Normal Breast tissue of Healthy Lactating Women Volunteers

Naranamangalam R Jagannathan 1 , Khushbu Agarwal 1 , Rani G Sah 1 , Uma Sharma 1 , Rajinder Parshad 2 , and Vurthaluru Seenu 2

1 Department of NMR & MRI Facility, All India Institute of Medical Sciences, New Delhi, Delhi, India, 2 Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, Delhi, India

Diffusion weighted imaging and in-vivo proton MRS in lactating women volunteers (n=16) and in patients with breast cancer (n=13) showed total choline peak in 16/16 malignant cases and in 11/13 lactating women volunteers. Further, 11/13 of lactating women showed a lactose peak at 3.8 ppm. tCho concentration was similar in both groups while higher ADC was observed in lactating women. Our study demonstrated that higher ADC value together with the presence of a lactose peak may aid in the differentiation of changes that occur in the breast tissues due to normal physiological conditions as compared with malignant transformations.

This abstract and the presentation materials are available to members only; a login is required.

Join Here