Clinical investigation of whole brain myelin water fraction imaging in patients with multiple sclerosis
Elizabeth Monohan 1 , Sneha Pandya 2 , Kyoko Fujimoto 1 , Thanh D. Nguyen 2 , Christopher Blackwell 1 , Nancy Nealon 1 , Jai S. Perumal 1 , Ashish Raj 2 , Tim Vartanian 1 , and Susan A. Gauthier 1
Neurology and Neuroscience, Weill Cornell
Medical College, New York, NY, United States,
Weill Cornell Medical College, New York, NY, United
The aim of this study was to apply a fast whole T2prep
3D spiral acquisition and a novel post-processing
algorithm to a cohort of 141 MS patients and assess its
capability in demonstrating the variability in myelin
content among lesions and normal appearing white matter.
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