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Abstract #0739

High-resolution diffusion weighted MRI enabled by multiplexed sensitivity-encoding using projection on convex set (POCSMUSE)

Mei-Lan Chu 1,2 , Hing-Chiu Chang 2 , and Nan-Kuei Chen 2,3

1 Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, Taiwan, 2 Brain Imaging and Analysis Center, Duke University, Durham, North Carolina, United States, 3 Department of Radiology, Duke University, Durham, North Carolina, United States

Diffusion-weighted imaging (DWI) data acquired with interleaved EPI sequence are highly susceptible to inter-segment phase variations and aliasing artifacts induced by motion in the presence of strong diffusion weighting gradients. Here we report a novel and efficient approach to remove aliasing artifacts in interleaved EPI based high-resolution DWI data through developing a MUSE algorithm based on projection onto convex set (POCS) 2. The new technique, termed POCSMUSE, can provide high-quality image without navigator echo, and can be generally applied to DWI data acquired with arbitrary k-space trajectory.

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