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Abstract #0705

Compression Effects in Breast MR Elastography

Jun Chen 1 , Kathleen Brandt 1 , Karthik Ghosh 1 , Roger Grimm 1 , Kevin Glaser 1 , Jennifer Kugel 1 , Kay Pepin 1 , and Richard Ehman 1

1 Mayo Clinic, Rochester, MN, United States

In conventional breast MR Elastography (MRE), the driver compresses the breasts to maintain mechanical coupling for wave transmission. This compression could introduce a significant bias into the measured stiffness of breast tissue. For the first time, this study reports strong evidence of breast compression effects in breast MRE. With 20% breast compression, glandular and adipose tissue stiffness increased by 53.8% and 103.8% respectively. Therefore, true breast tissue stiffness can be measured only when there is no compression, such as when using the noncompressive breast MRE technique utilized in this study.

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