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Abstract #0639

Characterizing electrical interactions of tissue with time-varying gradient fields: simulations and measurements

Stefano Mandija 1 , Astrid L.H.M.W. van Lier 1 , Axel Thielscher 2,3 , Andre Antunes 4 , Sebastiaan F.W. Neggers 5 , Peter R. Luijten 1 , and Cornelis A.T. van den Berg 1

1 Imaging Division, University Medical Center, Utrecht, Netherlands, 2 Danish Research Centre for Magnetic Resonance, Copenhagen, Denmark, 3 Technical University of Denmark, Kgs. Lyngby, Denmark, 4 Max Planck Institute for Biological Cybernetics, Tbingen, Germany, 5 Rudolf Magnus Institute of Neuroscience, University Medical Center, Utrecht, Netherlands

At low frequency (Hz-kHz) the human body is electrically very heterogeneous. Adjacent biological structures constitute strong electrical impedance variations that affect current flow. In this work, we studied the effect of electrical impedance variations on the magnetic field distortions by inducing eddy currents caused by the readout gradient. We performed simulations and measurements on saline phantoms. We saw that, by measuring the induced Bz field, it is possible to derive information about the electric conduction and composition of media, e.g. interfaces and their orientation.

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