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Abstract #0557

CT-like 3D Isotropic Fat-Suppressed Dynamic Contrast Enhanced MR Enterography

Ivan E. Dimitrov 1,2 , Ananth J. Madhuranthakam 2,3 , Qing Yuan 3 , William A. Grissom 4,5 , Takeshi Yokoo 2,3 , and Ivan Pedrosa 2,3

1 Philips Medical Systems, Cleveland, OH, United States, 2 Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States, 3 Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States, 4 Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, 5 Radiology, Vanderbilt University, TN, United States

Acquisition of clinical dynamic contrast-enhanced (DCE) MR Enterography is challenged by: (1) need for breath-held high-resolution imaging of the entire abdomen and pelvis; (2) homogenous fat suppression over large FOVs; (3) preferred positioning of patients arms along the side of the abdomen to increase compliance. To address these challenges we combine: (a) massive parallel imaging acceleration in two directions; with (b) aggressive reduction of the left-to-right FOV with suppression of out-of-FOV signals by combining sagittal 3D excitation for coronal imaging with custom-designed RF pulses having near-zero stopband excitation. These pulses allow for shorter TEs such that the mathematical conditions for proper DIXON-based water/fat separation are maintained. High-resolution fat-suppressed 3D isotropic, CT-like DCE acquisitions of the abdomen/pelvis were achieved.

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