Abstract #0524
In vivo T 2 * effect on pharmacokinetic parameter estimation using reference tissue arterial input function at 7T
Jin Zhang 1 , Melanie Freed 1 , Kerryanne Winters 1 , and Sungheon Kim 1
1
Radiology, New York University, New York,
New York, United States
The influence of T
2
*
on
lesion signal intensity and arterial input function at
high field can induce systemic errors in pharmacokinetic
parameter estimation. When the arterial input function
is estimated from reference tissue, the T
2
*
effect
on parameter estimation may be relatively smaller than
when it is directly measured. In this study, we
investigate the influence of a Gd-based contrast agent
on the T
2
*
of
tumor at 7T and its effect on kinetic model analysis.
Our preliminary results show no significant difference
between pharmacokinetic model parameters from T
2
*
-corrected
and non-corrected data when a reference tissue arterial
input function is used.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
