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Abstract #0508

Simultaneous fat, water and T2* mapping of trabecular bone and comparison with high resolution MRI in the hip

Pippa Storey 1 , Gregory Chang 1 , Stephen Honig 2 , Kashif Khokhar 1 , Mary T. Bruno 1 , David R. Stoffel 1 , and Sandra L. Moore 1

1 Radiology Department, New York University School of Medicine, New York, NY, United States, 2 Division of Rheumatology, New York University School of Medicine, New York, NY, United States

Destruction of trabecular bone can result from osteoporosis or malignant processes, and is difficult to characterize adequately using conventional methodologies. We compared simultaneous fat, water and T2* mapping with high resolution trabecular imaging in the hips of 30 patients with osteoporosis or osteopenia. T2* is known to be sensitive to trabecular density since the magnetic susceptibility of mineralized bone differs from that of marrow. In addition, fat content may potentially allow discrimination of osteoporosis from malignant infiltration. Elevated T2* was found to be correlated with trabecular paucity, both in terms of anatomic distribution and across patients (Spearman r=0.64, p=0.00014).

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