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Abstract #0453

Assessment of renal allograft function early after transplantation with diffusion tensor imaging

Wenjun Fan 1,2 , Panli Zuo 3 , and Wen Shen 1

1 Radiology, Tianjin First Center Hospital, Tianjin, Tianjin, China, 2 Armed Police Corps Hospital of Henan, Zhengzhou, Henan, China, 3 Siemens Healthcare, MR Collaborations NE Asia, Beijing, China

51 renal allograft recipients 2-3 weeks after transplantation and 26 healthy volunteers received 3.0T MR DTI examination. Patients were divided into three groups with good allograft function, moderately impaired allograft function and severely impaired allograft function according to the estimated glomerular filtration rateApparent diffusion coefficient (ADC) and fractional anisotropy (FA) values were compared between groups with significant differences being found. A significant correlation between eGFR and medullary FA, cortical ADC and medullary ADC was also observed. Meanwhile, differences of DTI images and tractography demonstrated the potential of DTI to visually discriminate allograft with varied function.

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