Assessment of renal allograft function early after transplantation with diffusion tensor imaging
Wenjun Fan 1,2 , Panli Zuo 3 , and Wen Shen 1
Radiology, Tianjin First Center Hospital,
Tianjin, Tianjin, China,
Police Corps Hospital of Henan, Zhengzhou, Henan, China,
Healthcare, MR Collaborations NE Asia, Beijing, China
51 renal allograft recipients 2-3 weeks after
transplantation and 26 healthy volunteers received 3.0T
MR DTI examination. Patients were divided into three
groups with good allograft function, moderately impaired
allograft function and severely impaired allograft
function according to the estimated glomerular
filtration rateApparent diffusion coefficient (ADC)
and fractional anisotropy (FA) values were compared
between groups with significant differences being found.
A significant correlation between eGFR and medullary FA,
cortical ADC and medullary ADC was also observed.
Meanwhile, differences of DTI images and tractography
demonstrated the potential of DTI to visually
discriminate allograft with varied function.
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