Abstract #0446
Resting State fMRI in the moving fetus: a robust framework for motion and spin history correction.
Giulio Ferrazzi 1,2 , Maria Kuklisova Murgasova 1,2 , Tom Arichi 3 , Joanna Allsop 1,2 , Christina Malamateniou 1,2 , Mary Rutherford 1,2 , Shaihan Malik 1,2 , Paul Aljabar 1,2 , and Joseph V. Hajnal 1,2
1
Center for the Developing Brain, King's
College London, London, United Kingdom,
2
Division
of Imaging Sciences & Biomedical Engineering, King's
College London, London, United Kingdom,
3
Department
of Bioengineering, Imperial College London, London,
United Kingdom
During typical fetal Resting State fMRI examinations,
maternal respiration and fetal movement together result
in large scale and unpredictable motion. Conventional
fMRI processing methods, which assume that brain
movements are infrequent or at least small, are not
suitable. We seek to address the problem of fetal motion
in fMRI using image registration to place the acquired
data into a self-consistent anatomical space. Bias field
and spin history corrections are also discussed, aiming
at achieving a robust framework that allows as much as
possible, ideally all acquired data, to be retained as
part of the final network analysis.
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