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Abstract #0398

A Wirelessly Programmable Implant Coil for Increased NMR Signal Sensitivity at Multiple Frequencies

Walker J. Turner 1 , Garrett W. Astary 2 , Barbara L. Beck 3 , Thomas H. Mareci 2 , and Rizwan Bashirullah 1

1 Electrical and Computer Engineering, University of Florida, Gainesville, FL, United States, 2 Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, United States, 3 Advanced Magnetic Resonance Imaging and Spectroscopy Facility, McKnight Brain Institute, University of Florida, Gainesville, FL, United States

We propose an implantable device capable of increasing the signal sensitivity of nuclear magnetic resonance (NMR) measurements at multiple frequencies and field strengths for use in monitoring bio-artificial organs post-implantation. The device enables complete wireless control of the resonance of a single-turn detection coil, coupled to the already existing NMR excitation/acquisition coil, across a wide range of frequencies associated with important metabolic nuclei in both 4.7Tesla and 11.1Tesla magnetic field strengths. Device functionality was validated through NMR experiments on tissue equivalent gel phantoms resulting in ~2x increase in NMR signal sensitivity.

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