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Abstract #0343

Multi-site, multi-vendor reproducibility of R2* relaxometry on an SPIO phantom at 1.5T and 3T

Diego Hernando 1 , Ihab Kamel 2 , Li Pan 3 , Ivan Pedrosa 4,5 , Shreyas Vasanawala 6 , Takeshi Yokoo 4,5 , Qing Yuan 4 , and Scott B. Reeder 1,7

1 Radiology, University of Wisconsin-Madison, Madison, WI, United States, 2 Radiology, Johns Hopkins University, MD, United States, 3 Corporate Technology, Siemens Corporation, Baltimore, MD, United States, 4 Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 5 Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States, 6 Radiology, Stanford University, CA, United States, 7 Medicine, University of Wisconsin-Madison, Madison, WI, United States

Recently developed R2* relaxometry techniques may enable rapid, accurate and robust liver iron quantification. However, the reproducibility of these techniques across multiple sites and MRI platforms has not been established, precluding their widespread dissemination. In this work, we studied the reproducibility of R2* mapping on a phantom with different iron concentrations, at four sites and on eight different scanning platforms including 1.5T and 3T. Results demonstrate excellent reproducibility across sites and platforms at each field strength over a wide range of R2* values.

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