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Abstract #0341

Maximizing Tissue Contrast in MRI Using RAFFn Preparation with SWIFT and Spin Echo Readouts

Timo Liimatainen 1 , Djaudat Idiyatullin 2 , Jinjin Zhang 2 , Hanne Hakkarainen 1 , Silvia Mangia 2 , Michael Garwood 2 , and Shalom Michaeli 2

1 A.I.Virtanen Institute, University of Eastern Finland, Kuopio, FI, Finland, 2 Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States

The general procedure of generating tissue contrast which is characterized predominantly by slow motion by altering steady state in SWIFT with RAFFn preparation pulses is described. It is shown that high rotating frame relaxation contrasts obtained with RAFFn provide enhanced sensitivity to slow motion in tissue and is associated with myelin in the brain.

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